Urinary Tract Infections on the Rise: Reasons, Options, Solutions

 

“Risk factors for fungal infections can vary; mRNA vaccines might be one of them.”

 

In clinical practice, urinary tract infections (UTIs) are a persistent concern for women, with many experiencing one or more episodes each year, often lasting several days. The reliance on antibiotics as the primary treatment option can be particularly stressful for those affected. Frequent antibiotic use may not only contribute to the recurrence of infections but also lead to reduced effectiveness over time, necessitating increasingly stronger treatments. Additionally, factors such as aging, the typical Canadian diet, side effects from mRNA jabs, abnormal stress, infections, genetic mutations, and caesarean delivery may result in deficiencies in essential trace minerals, further increasing susceptibility to infections, or even create lifelong bacterial infections. UTI infections have been also associated with a weakened immunity  and it is also known that “[m]ore than 80% of urinary tract infections (UTIs) in healthy individuals are caused by uropathogenic Escherichia coli (UPEC) that originate from the gut.”[1]

Fungal urinary tract infections, COVID-19 and mRNA connections

Candida species, typically opportunistic pathogens naturally present in the human body, have become significant contributors to nosocomial infections, particularly Candida albicans and emerging non-albicans species like Candida auris. Candiduria—the presence of Candida in urine—poses diagnostic and therapeutic challenges, as it can indicate anything from sample contamination to severe infections such as disseminated candidiasis. Candida auris, first identified in 2009, is a growing global concern due to its resistance to multiple antifungal agents, high mortality rates, and difficulty in microbiological identification, making it a critical emerging pathogen in healthcare settings.

Lately, the issue we are finding in many people is the low level of bacterial resistance. This stems from a weakening immune system created by dysbiosis, an imbalance of gut bacteria, which occurs when there are too many harmful bacteria but too few beneficial ones, or a loss of overall diversity. COVID-19–induced intestinal barrier dysfunction and gut-lung dysbiosis significantly impacted immune homeostasis, contributing to systemic and respiratory bacterial and fungal infections. Severely ill COVID-19 patients experienced a higher incidence of Candida bloodstream infections due to an accumulation of traditional risk factors. Additionally, outbreaks of the highly clonal Candida auris were reported globally, with cases of colonization and infection primarily linked to nosocomial transmission, setting it apart from other Candida species. According to a review published in Current Fungal Infection Reports “[i]nfections due to Candida species in severely ill COVID-19 patients reflected the overall immune dysregulation and were largely driven by gut and respiratory tract dysbiosis.”[2]

Candida auris poses a significant risk to individuals who are already seriously ill or immunocompromised, particularly those in hospitals and nursing homes. Mortality rates for invasive infections are estimated to be over 40%, according to the Public Health Agency of Canada (PHAC). The potential for outbreaks in healthcare and long-term care facilities raises concerns, prompting experts to emphasize the importance of surveillance, early diagnosis, and testing to prevent further spread. Healthy individuals typically do not become seriously ill with the pathogen. However, the ease with which Candida auris spreads, living on surfaces and being challenging to clean, poses a significant challenge.[3]

Risk factors for fungal infections can vary; mRNA vaccines might be one of them. “[A]dverse effects following vaccination have been noted which may relate to a proinflammatory action of the lipid nanoparticles used or the delivered mRNA (i.e., the vaccine formulation), as well as to the unique nature, expression pattern, binding profile, and proinflammatory effects of the produced antigens – spike (S) protein and/or its subunits/peptide fragments – in human tissues or organs.”[4]

The problem with current treatments

Does healthcare provide a proper solution for UTIs? Not really. Recently, the U.S. Food and Drug Administration has approved Orlynvah (sulopenem etzadroxil and probenecid) oral tablets for the treatment of uncomplicated urinary tract infection(s) even though “[c]linical trials evaluating Orlynvah for the treatment of patients with cUTI and cIAI did not demonstrate effectiveness.”[5] On the other hand, there are several side effects; the most common ones are diarrhea, nausea, vaginal yeast infection, headache, and vomiting.

Meanwhile, according to new research, “primary care physicians are generally comfortable prescribing vaginal estrogen therapy for recurrent urinary tract infections (UTIs), other nonantibiotic prophylactic options remain significantly underutilized. (…) Researchers at the University of North Carolina surveyed 40 primary care physicians at one academic medical center and found that 96% of primary care physicians prescribe vaginal estrogen therapy for recurrent UTI prevention, with 58% doing so “often.””[6] The problem with this treatment is the amount of side effects, especially for breast cancer survivors.

Natural health solutions

Fortified Boron can naturally boost estrogen levels without side effects. Boron can improve the production of estrogen in menopausal women, and can bring back their sex drive within a few days of treatment. It increases the level of natural sex hormones in the body, thereby reducing the need for hormone replacement therapy or other pharmaceutical solutions.

Other effective strategies and methods can boost immune defenses to contain or prevent urinary tract infections. Doctor’s Choice® UTI Health can be one of them.

  • when taken daily helps prevent/reduce the risk of recurrent UTIs in women
  • helps to produce and repair connective tissue
  • helps to prevent manganese deficiency
  • helps to maintain normal iron transport in the body
  • helps to form red blood cells
  • helps in the development and maintenance of bones

The medical ingredients include copper, manganese, D-mannose and cranberry juice powder.

  • Cranberries contain two compounds with anti-adherence properties that prevent fimbriated Escherichia coli from adhering to uroepithelial cells in the urinary tract.
  • D-mannose, a variety of sugar related to glucose and found in several fruits, may have the ability of preventing certain kinds of bacteria from sticking to the walls of the urinary tract and causing infection.
  • Copper, lacking trace minerals can create the bedding ground for infections. One that is typically lacking is copper which is known to resist infections and bacterial growth.
  • “Manganese plays an essential role in many cellular processes including lipid, protein, and carbohydrate metabolism. It also contributes to protection against oxidative stress, is a cofactor for a number of enzymes in bacteria and other organisms, and can also contribute directly to the catalytic detoxification of reactive oxygen species.”[7]

Doctor’s Choice Immunity Protocol: 

CLAW Therapy: 3 capsules 2 times per day. An oral chelation therapy with medicinal grade EDTA designed to safely remove heavy metals from the body.  Graphene oxide creates a heavy metal toxic load and creates oxidative stressors that contribute to the accumulation of radiation, viruses, environmental toxins and household chemicals, heavy metals (such as graphene). Increased incidence of thyroid disease can be linked to an over-burden of toxins by pollution.

Opti Cal/Mag with K2: 2 capsules 2 times per day. Prevents the healing crisis while taking CLAW Therapy by replacing chelated minerals, best taken four hours before or after CLAW Therapy.

Melapure® Melatonin: Patented, USP Pharmaceutical Grade: 30mg per day taken two hours before bed. Melapure is a powerful antioxidant and a biocompatible competitor of hydrazine in reduction of graphene oxide (GO). Melatonin is a chronobiotic, that is, an agent that can cause adjustments of the body clock. It is also cyto-or cell protective and can reverse the inflammation typically seen in neurodegenerative disorders and aging. Melatonin is a potent antioxidant that aids the detoxification of the brain through the glymphatic system (the brain’s waste disposal apparatus that work while you sleep).

Thymus Gland: 3 capsules 3 times per day taken on an empty stomach. The thymus gland produces T-cells, our body’s immune defence, and plays a significant role in the regulation of adaptive immune responses. Overall T-Cell levels are maintained by peripheral thymus-independent homeostatic mechanisms, memory T-Cells stimulated by cytokines undergo proliferation and differentiation. Boosting the immune system by incorporating thymus gland can be a therapeutic strategy for preventing virus-related diseases. Insufficiencies of the thymus gland may lead to abnormal thymic function the incorporation may be an intrinsic factor for treating severe long term COVID disease among younger individuals. Patients’ overall health may be incorporated using thymus gland in COVID-19 management.

L-Glycine (fermented), for severe Covid-19: 2 capsules taken 3 times per day with Thymus Gland. The amino acid glycine is for the biosynthesis of heme (iron), a key component of haemoglobin, essential for red blood cell integrity and optimal oxygen capacity. Glycine is the major agonist of glycine receptors (GlyR), which are chloride channels that hyperpolarize cell membranes of inflammatory cells such as macrophages and neutrophils, turning them less sensitive to proinflammatory stimuli. In addition, glycine possesses a cytoprotective effect, improves endothelial function, and diminishes platelet aggregation.

Immunity 4 in 1: (USP grade material). 2 capsules 3 times per day with food. A single ingredient is rarely as effective as when taken with supportive synergistic nutrients. “There is evidence that quercetin in combination with, vitamins C and D, may exert a synergistic antiviral action that may provide either an alternative or additional therapeutic/preventive option due to overlapping antiviral and immunomodulatory properties.” Immunity 4 in 1 contains pure vitamin C (certified non-GMO), a powerful detoxing agent against heavy metal poisoning, useful for graphene oxide removal; pure vitamin D, a new study for Long Covid is suggesting that vitamin D supplements may help prevent or ease the debilitating condition; quercetin, a flavonoid which is antiviral and anti-inflammatory. The literature reveals that quercetin exhibits anti-COVID-19 activity because of its inhibitory effect on the expression of the human ACE2 receptors and the enzymes of SARS-CoV-2, and citrus bioflavonoids; flavonoids interact with ACE1 and ACE2 receptors, inhibit their activity and have an antiviral effect.

Laktokhan Probiotic Complex: 1 capsule before breakfast and dinner. The immune health of the gut lining, the mucosal layer within the gut, influences your intestinal flora and your entire immune system. This protective barrier separates what you consume and the inner intestinal wall.  The mucosal layer within the gut influences your intestinal flora and your entire immune system. This protective barrier separates what you consume and the inner intestinal wall. This barrier contains an immune compound called secretory immunoglobulin A (IgA/sIgA) which is critical for healthy intestinal flora; it is an antibody that helps trap foreign substances, preventing them from adhering to the inner gut wall. This process protects the tight junctions inside the gut from oxidative stress caused by germs, heavy metals, and other unwanted substances from entering circulation.

Zinc Picolinate: 1 capsule twice per day taken with food. Picolinates are part of the body’s natural chelation process, they are more readily recognized and used by the cells. Zinc is involved in more than 200 enzymatic reactions and plays a key role in genetic expression, cell division, and growth. Zinc picolinate act as antiviral against many RNA viruses including SARS-CoV-2.

Raw desiccated Thyrodine® Thyroid Gland Complex: 1 capsule in the morning and 1 in the afternoon, taken on an empty stomach. Thyroid is running close to epidemic levels, affecting radiation toxicity and hormone imbalance. The thyroid gland regulates innate and adaptive immune systems by genomic and nongenomic pathways. During or after SARS-CoV-2 infection, Graves’ disease and subacute thyroiditis might be triggered resulting in hyperthyroidism; alternatively, the effect of the virus on the hypophyseal.hypothalamic axis might cause central hypothyroidism. Severe cases of coronavirus disease 2019 (COVID-19) can present with hypoxia (low levels of dissolved oxygen). The primary hypothesis is the direct influence on the thyroid gland by SARS-CoV-2 causing euthyroid sick syndrome (ESS), resulting in decreased levels of serum T3 and/or T4 without increased secretion of TSH. In patients with COVID-19, ESS may be directly caused by the infection of thyroid cells with SARS-CoV-2. Thyroid dysfunction maybe caused by direct infection of the thyroid or a “cytokine storm”-mediated autoimmune effect on the thyroid,

HEALTH DISCLAIMER:

The information provided is not meant to substitute for the advice provided by your doctor or other health care practitioner. Information and statements regarding dietary supplements have not been evaluated by Health Canada or the Food and Drug Administration.

References:

  • Abraham, Soman N. – Miao, Yuxuan. 2015. The nature of immune responses to urinary tract infections. Nat Rev Immunol. 15(10): 655–663.
  • Porcheron, Gaëlle et al. 2013. Iron, copper, zinc, and manganese transport and regulation in pathogenic Trougakos, Ioannis P et al. 2022.Enterobacteria: correlations between strains, site of infection and the relative importance of the different metal transport systems for virulence. https://www.frontiersin.org/articles/10.3389/fcimb.2013.00090/full

[1] Abraham, Soman N. – Miao, Yuxuan. 2015.

[2] Kordalewska, Milena and Perlin, David S. 2023.

[3] Lee, Jennifer. 2023.

[4] Trougakos, Ioannis P et al. 2022.

[5] U.S. Food and Drug Administration. 2024.

[6] Salahi, Lara. 2024.

[7] Porcheron, Gaëlle et al. 2013.