Preventing Premature Aging
“The key to preventing premature aging is by first understanding how the body’s systems start breaking down with age, this implementation can significantly lessen the impact of the aging process.”
Aging gracefully is a blessing but aging prematurely is not. The key to the aging process may lie within our endocrine system, primarily the pituitary, thymus, thyroid, adrenals, and the pineal gland in conjunction with a lack of trace minerals.
There are several factors that can accelerate the aging process: environmental toxins, genome deterioration—which includes DNA damage from experimental medical procedures, including genetic code modification—and from ionizing and ultraviolet radiation, including solar flares. Epigenetic factors also contribute to the aging process from lifestyle, diet, lack of exercise, smoking and mental health disorders. Then there is telomere shortening. Telomeres form the ends of human chromosomes and they play an important role in making sure your DNA gets copied properly when cells divide. Telomeres can act as tumor suppressors but they can change during the premature ageing process and disease being associated with increased cancer risks.
Mitochondrial dysfunction may also occur, due to disease or toxic overload from chemical toxicity, certain pharmaceutical drugs, or genetic abnormalities. In addition, we also need to mention stem cell exhaustion—when tissues and organs lose their ability to recover from damage and begin to fail—this happens to the multipotent stem cells in the fat tissue, dental pulp, heart tissue, and for immunity bone marrow, thus limiting the selection of various cell types.
Modern science is an expert for what it knows rather than what it does not. For the scientific advancement towards longevity, one may first need to examine inwardly our intricate design rather than introducing foreign matter or drugs within our beings. Advancement through the lowest levels of magnification could open many new discoveries. I like to think of the body as a fine Swiss watch, the time is displayed (age) and the hands turn (daily life) and everything on the surface appears normal in the process. The question is whether the timing is accurate. A craftsman will first examine every movement (causal chain), and after full inspection make hair like adjustments until the timing becomes perfect. Medical science has forgotten this approach with synthetic chemical based allopathic prescription drug medicine.
The medical community will say that these declines should be accepted as the natural process of getting older that will continue until death. I have a problem with accepting this gradual surrender of my facilities in preparation for a decline of my eye sight, memory, attention, muscle tone, and the acceptance of living with pain. Sleeping through the night? No, this also changes to getting up in the middle of the night to pee—everyone your age is doing it but is it normal? I do not think so. I get told quite often that I am looking good, with the added reference for your age, while I am thinking in my head: compared to what?
The key to preventing premature aging is by first understanding how the body’s systems start breaking down with age, and how, before the decline, through prevention replacement of the lost nutrients, this implementation can significantly lessen the impact of the aging process.
What we know is that the brain peaks at about thirty years of age then slowly begins its decline; the pituitary gland located at the base of the brain releases growth hormone (GH), the one piece of the endocrine system controlled by the brain. The pituitary gland is no larger than a pea, it regulates growth, metabolism, and reproduction via the hormones produced; these hormones are chemical messengers from the hypothalamus to the pituitary gland (both attached), producing two hormones: vasopressin and oxytocin.
Your thymus gland (which produces T-cells, your immune defense) begins its decline in your early twenties. Many in the field of anti-aging believe that the thymus gland may be the key to the aging process and they may not be wrong in their assessment. Your pineal gland—serotonin/melatonin—begins to decline from age fifty, leading to age related insomnia, depression, and mental illness.
Just when we need our glands to be their strongest, they begin their decline. Preventing premature aging begins with the pituitary gland—it is critical. The younger a person is, the higher the GH levels are, and the more efficiently they function. As we mature, our bodies begin recognizing that the growth process is over while reducing the production of GH.
Growth Hormone Deficiency (GHD) is a condition in which a person’s anterior pituitary gland fails to produce an adequate amount of normal endogenous growth hormone. In children, it results in dwarfism; in adults, GHD causes deficiencies including loss of muscle and increase of fat, decreased healing ability, a greater risk of cardiovascular disease, loss of bone mass and lower life expectancy—in other words symptoms commonly associated with aging.
If the pituitary gland is out of balance, the fallout affects all endocrine gland hormones. Like dominoes, they all begin to fail; the pituitary – endocrine balance regulates the thyroid, adrenals, thymus, pineal gland, sex hormones; estrogen and testosterone and the pancreas. The pineal gland regulates the release of the serotonin-derived hormone melatonin, responsible for regulating the circadian cycle for the sleep-wake cycle; 95% of the total serotonin in the body is within the gut, also known as the second brain. The thyroid gland controls metabolism. The adrenal system controls inflammation, infection, and of course, adrenaline production. The thymus controls immunity by producing T-cells for maintaining natural immunity to fight off infection. The pancreas produces insulin, which regulates blood sugar and digestive enzymes. The aging hippocampus is influenced by increased oxidative stress and neuroinflammation, the process whereby the brain’s innate immune system (protects against antigens) and the importance of maintaining natural immunity is triggered due to injury, infection, exposure to a toxin, neurodegenerative disease, or premature aging.
New science has emerged from Japan revealing that low dose lithium can prevent telomere shortening in cortical neurons with a 4—7 fold increase in telomere length; it is great news and another key element that may prevent several degenerative diseases, such as mental illness.
Research shows that daily low dose of lithium may have a beneficial impact on mental and physical health and possibly increase longevity. Lithium’s impact may be due to its inhibition of an enzyme in the body known as glycogen synthase kinase-3 (GSK-3). Lithium promotes longevity through GSK3, GSK-3 overactivity has been tied to rapid aging and risk for chronic diseases. Studies suggest that GSK-3 inhibition is largely responsible for lithium’s ability to protect brain function and extend lifespan.
Therapeutic nutraceutical medicine has made great strides in discovering anti-aging solutions yet they rarely made available to the health food industry for several reasons. Anti-aging research and development is my field of specialty, one of the main obstacles is ownership if non-patentable, after successful federal licensing is granted. Lack of strong medicinal claims for natural medicine requires a lengthy education process to successfully bring the product to market. Novel formulas can be easily copied and it is very frustrating. We have introduced several unique formulations only to find a copycat version with no intellectual investment selling more volume with questionable quality—Kava Kava is a perfect example.
As the mind is the director of change you must bring it into a state of awareness for changes to happen, the areas of the brain that deals with memory processing is the hippocampus and it is negatively affected by stress.
Reversing premature aging is possible at any age through intervention of lifestyle changes, exercise, proper sleeping patterns, change of diet, proper hydration and in replacing the missing nutrients, trace minerals and vitamins and to bring your body into a state of natural balance.
Preventing Premature Aging Protocol:
- HGH+ (GH): 8 drops under the tongue 3 times per day – taken on an empty stomach 20 minutes before or after food or water.
- Adrenal Gland: 2 capsules before breakfast and 2 capsules midday at approximately 2:00pm.
- Thyrodine® Thyroid Gland: 1 capsule in the morning and 1 capsule in the afternoon, separated by 8 or more hours.
- Sweet Dreams Melapure® Melatonin (serotonin): 1 mg (7 drops) before bed on an empty stomach.
- Thymus Gland (immunity): two capsules two times per day with food, for immune building three capsules three times per day.
- Laktokhan Probiotic Complex (gut, second brain, bacterial balance): 1 capsule 15 minutes before breakfast and dinner.
- L-Glycine (glycogen): One capsule three times per day with food.
- Lithium Homeopathic (telomeres): 30 drops two times per day, taken on an empty stomach 20 minutes before or after food or water.
- Neurotransmitter Support (increased neuronal activity): 2 to 3 capsules in the morning taken on an empty stomach. For early dementia, 3 capsules 3 times per day.
References and further readings:
- Castillo-Quan, Jorge Iván et al. 2016. Lithium Promotes Longevity through GSK3/NRF2-Dependent Hormesis. Cell reports 15,3: 638-650. doi:10.1016/j.celrep.2016.03.041
- DiSabato, Damon J et al. 2016. Neuroinflammation: the devil is in the details. Journal of neurochemistry 139 Suppl 2, Suppl 2: 136-153. doi:10.1111/jnc.13607
- a. 2021. What is a telomere? https://www.yourgenome.org/facts/what-is-a-telomere/
- Stolzing, Alexandra PhD. 2022. Stem cell exhaustion. https://www.lifespan.io/topic/stem-cell-exhaustion/
- Themoteo, Rafael M. et al. 2023. Lithium Prevents Telomere Shortening in Cortical Neurons in Amyloid-Beta Induced Toxicity. NeuroSci, 4(1), 1-8; https://doi.org/10.3390/neurosci4010001
 Stolzing, Alexandra PhD. 2022.
 DiSabato, Damon J et al. 2016.
 Themoteo, Rafael M. et al. 2023.
 Castillo-Quan, Jorge Iván et al. 2016.